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Available data

Data released with the package

fit_example
Example MOBSTER fit.
LU4_lung_sample
MOBSTER fit for the LU4 lung sample.
LUFF76_lung_sample
MOBSTER fit for the LUFF76 lung sample.
cancer_genes_dnds
List of cancer genes to compute dnds values.

Fitting functions

Functions to cluster the data; density of a mobster fit and sampling functions.

mobster_fit()
Fit a model with MOBSTER.
choose_clusters()
Filter MOBSTER output clusters.
Clusters()
Return the data with the hard clustering assigments.
Clusters_denovo()
Assign new observations to the clusters inside a MOBSTER fit.
ddbpmm()
Density function for MOBSTER.
rdbpmm()
Generate a random sample from a MOBSTER model.
random_dataset()
Generate a random MOBSTER model and data.
to_string()
Return a tabular representation of a model.

S3 functions

The mobster S3 object.

print(<dbpmm>)
Summaries for an object of class 'dbpmm' is like a print.
summary.dbpmm()
Summary for an object of class 'dbpmm' is a print.
plot.dbpmm()
Plot a MOBSTER fit.

Plotting functions

These functions can be used to plot data and mobster fits.

plot_NLL()
Plot the NLL trace.
plot_entropy()
Plot the entropy of a MOBSTER mixture.
plot_fit_scores()
Plot the scores for model selection.
plot_gofit()
Plot the goodness of fit.
plot_init()
Plot the initial density of a fit.
plot_latent_variables()
Plot the latent variables of the mixture.
plot_mixing_proportions()
Plot the mixing proportions of the mixture.
plot_model_selection()
Plot summary for model selection.

Bootstrap functions

Bootstrap functions for mobster fits, and plotting functions.

mobster_bootstrap()
Bootstrap a MOBSTER fit.
bootstrapped_statistics()
Compute boostrap statistics from a bootstrap run.
plot_bootstrap_Beta()
Plot the boostrapped tail parameters.
plot_bootstrap_coclustering()
Plot the boostrapped co-clustering probability.
plot_bootstrap_mixing_proportions()
Plot the boostrapped mixing proportions
plot_bootstrap_model_frequency()
Plot the boostrapped model frequency
plot_bootstrap_tail()
Plot the boostrapped tail parameters.

Extra features

Other analyses for mobster fits.

dnds()
Run a dN/dS analysis on MOBSTER clusters.
evolutionary_parameters()
Extract evolutionary parameters from a MOBSTER fit
get_clone_trees()
Return clone trees from the fit.
load_vcf()
Load data from a VCF file