List of gene ids (HuGO format) to compute dnds values. There are 2 lists available of putative driver genes, and 2 lists of essential genes; these lists have been subset to include only genes in the RefCDS database.
Drivers have been compiled in `Martincorena, et al. Cell 171.5 (2017): 1029-1041`, and in `Tarabichi, et al. Nature Genetics 50.12 (2018): 1630`. Essential genes have been compiled using two different cell lines in `Wang et al. Science 350.6264 (2015): 1096-1101.` and `Bloomen et al. Science 350.6264 (2015): 1092-1096`. All lists are available and named accordingly; use `names(cancer_genes_dnds)` to see the available names.
Usage
data(cancer_genes_dnds)Examples
data(cancer_genes_dnds)
print(lapply(cancer_genes_dnds, head))
#> $Martincorena_drivers
#> [1] "CCDC6" "EIF1AX" "HIST1H2BD" "MED12" "POLE" "SMARCB1"
#>
#> $Tarabichi_drivers
#> [1] "ACVR1" "ACVR1B" "AKT1" "ALK" "AMER1" "APC"
#>
#> $Wang_essentials
#> [1] "ABL1" "RPL23A" "AARS2" "TRMT112" "FARSA" "ABCB7"
#>
#> $Bloomen_essentials
#> [1] "AARS" "AASDHPPT" "AATF" "ABCB7" "ABCE1" "ABCF1"
#>