tickTack is a package to infer kinetic parameters of an evolving population whose size is observed at discrete intervals of time. The tool is able to
time simple CNAs for each segment affected by them
time CNAs in a hierarchical fashion, grouping together segments that most likely underwent a CNA concurrently
Citation
If you use tickTack, please cite:
- Timing and clustering co-occurring genome amplifications in cancers Sara Cocomello, Giovanni Santacatterina, Riccardo Bergamin, Alice Antonello, Giulio Caravagna. biorXiv 2025.
Installation
You can install the released version of tickTack from GitHub with:
# install.packages("devtools")
devtools::install_github("caravagnalab/tickTack")
