Available data

Example fit data, and data sampler.

fit_example

Example TINC fit

random_TIN()

Generate a random dataset for TINC.

Data processing

Functions to pre-process the data, mainly parsers.

load_TINC_input()

Load TINC input data.

load_VCF_Canvas()

Canvas VCF parsing function

load_VCF_Canvas_Manta()

Merged Canvas and Manta VCF parsing function

load_VCF_Strelka()

Strelka 2 VCF parsing function

load_VCF_CNA_DRAGEN()

DRAGEN VCF CNA parsing function

load_VCF_smallVar_DRAGEN()

DRAGEN VCF small variants parsing function

Data analysis

Functions to analyse the data, and plot results.

autofit()

Runs a TINC analysis.

to_string()

Dataframe description of a TINC fit

plot_simple_report()

Plot a strip short report of the TINC analysis.

plot_full_page_report()

Plot a full page detailed report of the TINC analysis

S3 functions

Functions to print and plot a tinc_obj

plot(<tin_obj>)

Plot a TINC analysis.

print(<tin_obj>)

Print a TINC object to screen

CHIP analysis

Functions to check for the presence of clonal hematopoiesis in normal/tumour bams

check_CHIP_variants()

Check for CHIP variants in normal and tumour at high VAF