Available dataData released with the package. |
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Multiome congas object |
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Dataframe containing cell type annotations for the 10x multiome lymphoma dataset. |
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Example tibbles with input ATAC data in the format for (R)CONGAS+ |
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Example tibbles with input RNA data in the format for (R)CONGAS+ |
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Main functionsFunctions to create and fit a dataset. |
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Format the input counts before creating the CONGAS+ object |
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Create a dataset. |
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Determine data-based hyperparameters for the Bayesian priors. |
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Compute empirical normalisation factors (library size) |
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Filter segments where the optimal number of clusters is 1. |
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Fit an (R)CONGAS+ model |
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GettersFunctions to extract information from a model. |
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Extract input data. |
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Extract fit data. |
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Compute the statistics of a dataset. |
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FilteringFunctions to pre-process inputs and post-process models. |
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Filter genes from an RNA tibble. |
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Filter observed counts by quantile. |
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Filter segments. |
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Filter per-segment outliers by quantiles. |
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Filter per-segment outliers by quantiles. |
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Plotting functionsFunctions to plot data and fits. |
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Plot data. |
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Plot fits. |
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S3 functionsThe |
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Print for an object of class |
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Plot for an object of class |
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Downstream analysesFunctions to perform additional analyses downstream of the CONGAS+ inference. |
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Build Clone Tree form a CONGAS+ object Using medicc2 |