Articles
Introduction
- Tissue simulation
Learn how to simulate tumour evolution
- Tissue sampling
How to sample cells from a simulated tissue
- Simulating Mutations
How to simulate mutations on sampled cells
- Sequencing Simulation
How to simulate sample sequencing
Advanced techniques
- Growth Models
What is a growth model and which growth models are implemented by rRACES
- Formula-based simulation constraints
Simulate a tissue evolution until a simulation state formula does not hold
- Customizing mutation engine
How to customize the mutation engine and its indices
- Infinite Site Model
How to enable/disable the infinite site model
- Partitioning samples (FACS)
How to partitioning samples, sorting cells, and simulate FACS
- Time Series Analysis
Analyse the evolution of the system over time
Tests and Examples
- A three-mutants sampling example
Sampling a three-mutants simulation
- SCOUT
The Simulated Cohort of Universal Tumours (SCOUT)