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Getting the sampled cells' CNAs

Source: R/RcppExports.R
PhylogeneticForest-cash-get_sampled_cell_CNAs.Rd

This method returns the CNAs of the sample cells.

Arguments

cell_id

The identifier of the cell whose CNAs are aimed (optional).

Value

A data frame reporting cell_id, type ("A" for amplifications and "D" for deletions), chr, begin (i.e., the first CNA locus in the chromosome), end (i.e., last CNA locus in the chromosome), allele, src allele (the allele origin for amplifications, NA for deletions), and class (i.e., "driver", "passenger", "germinal" or "preneoplastic").

Details

This method builds a data frame representing all the CNAs in the cells sampled during the simulation and represented by the leaves of the phylogenetic forest.

See also

PhylogeneticForest$get_sampled_cell_mutations()

Examples

sim <- TissueSimulation()

sim$add_mutant(name = "Clone_1",
               epigenetic_rates = c("+-" = 0.01, "-+" = 0.01),
               growth_rates = c("+" = 0.2, "-" = 0.08),
               death_rates = c("+" = 0.05, "-" = 0.01))
sim$place_cell("Clone_1+", 500, 500)
sim$run_up_to_size("Clone_1-", 1000)
#> 
 [████████████████████████████████████████] 100% [00m:00s] Saving snapshot                         


sim$sample_cells("Sample_A", c(475, 475), c(525, 525))
sample_forest <- sim$get_sample_forest()

m_engine <- MutationEngine(setup_code = "demo")
#> Downloading reference genome...
#> Reference genome downloaded
#> Decompressing reference genome...done
#> Downloading signature files...
#> Signature file downloaded
#> Downloading driver mutation file...
#> Driver mutation file downloaded
#> Decompressing driver mutation file...done
#> Downloading passenger CNAs file...
#> Passenger CNAs file downloaded
#> Decompressing passenger CNAs file...done
#> Downloading germline...
#> Germline downloaded
#> Decompressing mutations...
#> done
#> Building context index...
#> 
 [█---------------------------------------] 0% [00m:00s] Processing chr. 22                        

 [████████████████████--------------------] 49% [00m:01s] Processing chr. 22                       

 [████████████████████████████████████----] 89% [00m:02s] Processing chr. 22                       

 [████████████████████████████████████████] 100% [00m:02s] Context index built                     

#> 
 [█---------------------------------------] 0% [00m:00s] Saving context index                      

 [████████████████████████████████████████] 100% [00m:00s] Context index saved                     

#> done
#> Building repeated sequence index...
#> 
 [█---------------------------------------] 0% [00m:00s] Reading 22                                

 [████████████████████████████████████████] 100% [00m:01s] Reading 22                              

#> 
 [████████████████████████████████████████] 100% [00m:01s] Reading 22                              

#> 
 [████████████████████████████████████████] 100% [00m:01s] Reading 22                              

#> 
 [████████████████████████████████████████] 100% [00m:01s] Reading 22                              

#> 
 [████████████████████████████████████████] 100% [00m:01s] Reading 22                              

#> 
 [████████████████████████████████████████] 100% [00m:01s] Reading 22                              

#> 
 [████████████████████████████████████████] 100% [00m:01s] Reading 22                              

#> 
 [████████████████████████████████████████] 100% [00m:01s] RS index built                          

#> 
 [█---------------------------------------] 0% [00m:00s] Saving RS index                           

 [█---------------------------------------] 0% [00m:00s] Saving RS index                           

 [██████████████████████████--------------] 64% [00m:02s] Saving RS index                          
done
#> 
 [████████████████████████████████████████] 100% [00m:02s] RS index saved                          

#> 
 [█---------------------------------------] 0% [00m:00s] Loading germline                          

 [████████████████████████████████████████] 100% [00m:00s] Germline loaded                         

#> 
 [█---------------------------------------] 0% [00m:00s] Saving germline                           

 [████████████████████████████████████████] 100% [00m:00s] Germline saved                          


m_engine$add_mutant("Clone_1", list("+" = c(SNV = 1e-7, indel = 1e-8),
                                    "-" = c(SNV = 3e-7, CNA = 1e-11)),
                    list(SNV("22", 10510210, "C", allele = 1),
                         CNA("D", "22", 5010000, 200000,
                                   allele = 1)))
#> 
 [█---------------------------------------] 0% [00m:00s] Retrieving "Clone_1" SIDs                 

 [█---------------------------------------] 0% [00m:00s] Found 22                                  

 [█---------------------------------------] 0% [00m:00s] Reading 22                                

 [██████████████--------------------------] 33% [00m:01s] Reading 22                               

 [██████████████████████████--------------] 64% [00m:02s] Reading 22                               

 [████████████████████████████████████████] 98% [00m:03s] Reading 22                               

 [████████████████████████████████████████] 100% [00m:03s] "Clone_1"'s SIDs validated              


m_engine$add_exposure(c(ID1 = 1, SBS1 = 0.5, SBS2 = 0.5))

phylo_forest <- m_engine$place_mutations(sample_forest, 1, 1)
#> 
 [█---------------------------------------] 0% [00m:00s] Placing mutations                         

#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
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#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "T[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>G]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>A]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "A[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> Warning: No mutations for context "G[C>T]G". Decrease `MutationEngine`'s parameter `context_sampling`.
#> 
 [████████████████████████████████████████] 100% [00m:00s] Mutations placed                        


mutations <- phylo_forest$get_sampled_cell_CNAs()

head(mutations)
#>   cell_id type chr   begin     end allele src.allele  class
#> 1      21    D  22 5010000 5209999      1         NA driver
#> 2     703    D  22 5010000 5209999      1         NA driver
#> 3    1191    D  22 5010000 5209999      1         NA driver
#> 4    1239    D  22 5010000 5209999      1         NA driver
#> 5    1297    D  22 5010000 5209999      1         NA driver
#> 6    1759    D  22 5010000 5209999      1         NA driver