From a cohort object, this function extracts the tibble of annotated driver events for a patient (either CCF or binary).
Drivers(x, p)
| x | A |
|---|---|
| p | The id of a patient in the cohort. |
Drivers data for a custom patient.
Other Getters:
CCF_clusters(),
CCF(),
Clonal_cluster(),
Data(),
ITransfer(),
Phylo(),
Samples(),
Subclonal(),
Truncal(),
get_features()
# Data released in the 'evoverse.datasets' data('TRACERx_NEJM_2017_REVOLVER', package = 'evoverse.datasets') Drivers(TRACERx_NEJM_2017_REVOLVER, 'CRUK0002')#> # A tibble: 7 x 12 #> id Misc patientID variantID is.driver is.clonal cluster cluster_size CCF #> <chr> <chr> <chr> <chr> <lgl> <lgl> <chr> <int> <chr> #> 1 __mu… CRUK… CRUK0002 RB1 TRUE FALSE 1 3 R1:0… #> 2 __mu… CRUK… CRUK0002 IKZF1 TRUE FALSE 1 3 R1:0… #> 3 __mu… Anno… CRUK0002 KRAS TRUE FALSE 1 3 R1:0… #> 4 __mu… CRUK… CRUK0002 MET TRUE TRUE 2 2 R1:0… #> 5 __mu… Anno… CRUK0002 TERT TRUE TRUE 2 2 R1:0… #> 6 __mu… CRUK… CRUK0002 NF1 TRUE FALSE 5 1 R1:0… #> 7 __mu… CRUK… CRUK0002 EP300 TRUE FALSE 6 1 R1:0… #> # … with 3 more variables: R1 <dbl>, R2 <dbl>, R3 <dbl>Drivers(TRACERx_NEJM_2017_REVOLVER, 'CRUK0008')#> # A tibble: 6 x 11 #> id Misc patientID variantID is.driver is.clonal cluster cluster_size CCF #> <chr> <chr> <chr> <chr> <lgl> <lgl> <chr> <int> <chr> #> 1 __mu… CRUK… CRUK0008 KEAP1 TRUE TRUE 2 5 R1:0… #> 2 __mu… CRUK… CRUK0008 STK11 TRUE TRUE 2 5 R1:0… #> 3 __mu… CRUK… CRUK0008 PRDM1 TRUE TRUE 2 5 R1:0… #> 4 __mu… CRUK… CRUK0008 U2AF1 TRUE TRUE 2 5 R1:0… #> 5 __mu… Anno… CRUK0008 MYC TRUE TRUE 2 5 R1:0… #> 6 __mu… CRUK… CRUK0008 ARID2 TRUE FALSE 3 1 R1:0… #> # … with 2 more variables: R1 <dbl>, R2 <dbl>