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Fit the mutations clustering

Usage

fit_mutations(
  x,
  vaf.df = NULL,
  infer_phylo = TRUE,
  min_frac = 0,
  max_IS = NULL,
  highlight = list()
)

Arguments

x

a mvnmm object.

vaf.df

dataframe with mutations data.

infer_phylo

a Boolean indicating whether to infer also the phylogenetic evolution per cluster of ISs.

min_frac

add

max_IS

add

highlight

add

Value

A mvnmm object with the additional list x.muts containing the estimated subclones from somatic mutations.