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Logistic regression of metastatic tropism based on INCOMMON classes.

Usage

met_tropism(x, gene, tumor_type, metastatic_site)

Arguments

x

An object of class 'INCOMMON' containing the classification results as produced by function classify.

gene

The gene on which patient's stratification is based.

tumor_type

The tumor type of patients to stratify.

metastatic_site

The target organ of metastatic diffusion.

Value

An object of class 'INCOMMON' containing an additional object survival. Logistic regression of metastatic tropism based on INCOMMON classes.

Examples

# First load example classified data
data(MSK_PAAD_output)
# Estimate the metastatic propensity associated with mutant TP53 with vs
# without CNA in BRCA, with respect to the Liver.
MSK_PAAD_output = met_tropism(x = MSK_PAAD_output, tumor_type = 'BRCA', gene = 'TP53', metastatic_site = 'Liver')
#> Joining with `by = join_by(id)`